Los hallazgos, publicados en la revista \u2018mSystems\u2019, sugieren la posibilidad de tratamientos probi\u00f3ticos para la aterosclerosis, la peligrosa acumulaci\u00f3n de grasas, colesterol y otras sustancias en las arterias que causan derrames cerebrales y ataques card\u00edacos y que est\u00e1 relacionada con el tabaquismo, la dieta, la edad y una serie de causas gen\u00e9ticas.<\/p>\n\n\n\n
Las dietas con alto contenido de alimentos de origen animal se han considerado durante mucho tiempo un factor de riesgo de enfermedades cardiovasculares, ya que dichas dietas son una fuente importante de trimetilamina (TMA) que es convertida por el h\u00edgado en otro compuesto, trimetilamina N-\u00f3xido (TMAO), que promueve la acumulaci\u00f3n de placa grasa en las arterias.<\/p>\n\n\n\n
\u201cLA CONEXI\u00d3N ENTRE EL TMAO Y LAS ENFERMEDADES CARDIOVASCULARES HA TENDIDO A CENTRAR LA CONVERSACI\u00d3N EN C\u00d3MO LAS DIETAS DE ORIGEN ANIMAL TIENEN CONSECUENCIAS NEGATIVAS PARA LA SALUD. PERO AL ANALIZAR LOS DATOS DE LOS ESTUDIOS FUNDAMENTALES DE LOS MICROBIOMAS INTESTINALES, DESCUBRIMOS EVIDENCIA DE QUE UN TIPO DE BACTERIA ASOCIADA CON EL CONSUMO DE CARNE PUEDE TOMAR EL TMA, AS\u00cd COMO LOS PRECURSORES DEL TMA, Y METABOLIZARLOS SIN PRODUCIR NING\u00daN TMAO. ESO SIGNIFICA QUE ESAS BACTERIAS EST\u00c1N, EN EFECTO, CORTANDO UN ESLAB\u00d3N CLAVE EN LA CADENA DE ENFERMEDADES CARDIOVASCULARES\u201d, EXPLICA LA AUTORA PRINCIPAL DEL ESTUDIO, VERONIKA KIVENSON.<\/p><\/blockquote>\n\n\n\n
Las bacterias son del g\u00e9nero \u2018Bilophila\u2019 y la evidencia sugiere que un c\u00f3digo gen\u00e9tico expandido permite que su metabolismo, a trav\u00e9s de una v\u00eda de desmetilaci\u00f3n, evite la producci\u00f3n de TMAO. Adem\u00e1s, la investigaci\u00f3n muestra que las dietas basadas en animales causan un r\u00e1pido aumento de la \u2018Bilophila\u2019 en el intestino.<\/p>\n\n\n\n
\u201cSE HA DEMOSTRADO QUE LOS ORGANISMOS EN EL EST\u00d3MAGO AFECTAN EL DESARROLLO DE UNA MIR\u00cdADA DE ESTADOS DE ENFERMEDAD. PERO LOS MECANISMOS (LO QUE REALMENTE EST\u00c1 SUCEDIENDO DETR\u00c1S DE LAS CONEXIONES ENTRE LA DIETA, LA SALUD Y LA MICROBIOTA) HAN SIDO GENERALMENTE DIF\u00cdCILES DE PRECISAR. SE NECESITA M\u00c1S INVESTIGACI\u00d3N SOBRE LA BIOLOG\u00cdA Y LA ECOLOG\u00cdA DE LAS C\u00c9LULAS DE \u2018BILOPHILA\u2019, PERO NUESTRO ESTUDIO PRESENTA UN MECANISMO CLARAMENTE DEFINIDO CON POTENCIAL PARA UN GRAN IMPACTO EN LA SALUD HUMANA\u201d, SE\u00d1ALA EL COAUTOR DEL ESTUDIO, STEVE GIOVANNONI.<\/p><\/blockquote>\n\n\n\n
Identificada hace solo 31 a\u00f1os en un ap\u00e9ndice infectado, \u2018Bilophila\u2019 es una varilla anaer\u00f3bica gram-negativa que se clasifica como un patobio, un organismo que normalmente tiene una relaci\u00f3n simbi\u00f3tica con su hu\u00e9sped, pero que puede llegar a ser causante de enfermedades en determinadas circunstancias. Est\u00e1 com\u00fanmente presente en los microbiomas de las personas que est\u00e1n sanas.<\/p>\n\n\n\n
\u201cLOS DATOS QUE HEMOS REVISADO MUESTRAN QUE HAY UNA CANTIDAD SIGNIFICATIVAMENTE MAYOR DE \u2018BILOPHILA\u2019 EN LOS MICROBIOMAS DE LAS PERSONAS SANAS EN COMPARACI\u00d3N CON LAS QUE PADECEN ENFERMEDADES CARDIOVASCULARES, Y QUE EL N\u00daMERO DE BILOPHILA AUMENTA EN RESPUESTA A UNA DIETA BASADA EN LA CARNE EN COMPARACI\u00d3N CON UNA DIETA BASADA EN LAS PLANTAS. NUESTROS HALLAZGOS SUGIEREN QUE EL PAPEL DE BILOPHILA EN EL MICROBIOMA Y EN LA SALUD HUMANA PODR\u00cdA DEPENDER DEL CONTEXTO ESPEC\u00cdFICO Y QUE SU POTENCIAL COMO PROBI\u00d3TICO QUE MITIGA EL PAPEL DE LOS PRODUCTOS ANIMALES EN LA ENFERMEDAD CARDIACA DEBER\u00cdA SER ESTUDIADO M\u00c1S A FONDO\u201d, CONCLUYE KIVENSON.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"
Los hallazgos, publicados en la revista \u2018mSystems\u2019, sugieren la posibilidad de tratamientos probi\u00f3ticos para la aterosclerosis, la peligrosa acumulaci\u00f3n de grasas, colesterol y otras sustancias en las arterias que causan derrames cerebrales y ataques card\u00edacos y que est\u00e1 relacionada con…<\/p>\n","protected":false},"author":1,"featured_media":2287,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-2286","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-salud"],"yoast_head":"\n
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